KDIGO 2024 recommends to use an external validated risk equation to estimate the absolute risk... How often you use risk equations? Which are the old and new kids on the block? May kidney failure ⚠️equations useful to anticipate acute settings in kidney care ?
The Kidney Failure Risk Equation (KFRE) score is a tool recommended by the KDIGO 2024 guidelines to estimate the absolute risk of kidney failure in patients with chronic kidney disease (CKD). This recommendation is based on external validations demonstrating the accuracy and clinical utility of these risk equations.
Frequency of Use of Risk Equations In clinical practice, the use of risk equations, including the KFRE, has become increasingly common. The primary application of the KFRE is in stratifying the risk of CKD progression, aiding in decision-making regarding therapeutic interventions and long-term care planning.
Old and New Tools Among the "old" risk equations, the MDRD and CKD-EPI are well-known for estimating the glomerular filtration rate (GFR). However, these tools have limitations in specifically predicting the risk of progression to kidney failure.
The KFRE represents a "new generation" of risk equations, offering a more accurate estimate by considering additional variables beyond GFR, such as albuminuria. Recently, enhanced versions of the KFRE have been developed, incorporating additional laboratory markers to further refine risk estimates.
Utility in Acute Settings Although the KFRE was primarily developed to predict the risk of CKD progression in chronic settings, there are studies exploring its utility in acute situations. In the context of acute kidney care, anticipating kidney failure events can improve clinical management and readiness for emergency interventions.
However, it is important to note that the application of the KFRE in acute settings is still a subject of research, and its use should be complemented by clinical assessment and other renal function markers.
Conclusion In summary, the KFRE is a valuable tool in nephrology practice for predicting the risk of CKD progression, as recommended by the KDIGO 2024 guidelines. Regular use can optimize patient management and plan early interventions. However, its applicability in acute settings should be evaluated cautiously and in conjunction with other clinical assessments.
I hope this response clarifies your questions about the utility of the KFRE score.
The Kidney Failure Risk Equation (KFRE) score is a tool recommended by the KDIGO 2024 guidelines to estimate the absolute risk of kidney failure in patients with chronic kidney disease (CKD). This recommendation is based on external validations demonstrating the accuracy and clinical utility of these risk equations.
Frequency of Use of Risk Equations
In clinical practice, the use of risk equations, including the KFRE, has become increasingly common. The primary application of the KFRE is in stratifying the risk of CKD progression, aiding in decision-making regarding therapeutic interventions and long-term care planning.
Old and New Tools
Among the "old" risk equations, the MDRD and CKD-EPI are well-known for estimating the glomerular filtration rate (GFR). However, these tools have limitations in specifically predicting the risk of progression to kidney failure.
The KFRE represents a "new generation" of risk equations, offering a more accurate estimate by considering additional variables beyond GFR, such as albuminuria. Recently, enhanced versions of the KFRE have been developed, incorporating additional laboratory markers to further refine risk estimates.
Utility in Acute Settings
Although the KFRE was primarily developed to predict the risk of CKD progression in chronic settings, there are studies exploring its utility in acute situations. In the context of acute kidney care, anticipating kidney failure events can improve clinical management and readiness for emergency interventions.
However, it is important to note that the application of the KFRE in acute settings is still a subject of research, and its use should be complemented by clinical assessment and other renal function markers.
Conclusion
In summary, the KFRE is a valuable tool in nephrology practice for predicting the risk of CKD progression, as recommended by the KDIGO 2024 guidelines. Regular use can optimize patient management and plan early interventions. However, its applicability in acute settings should be evaluated cautiously and in conjunction with other clinical assessments.
I hope this response clarifies your questions about the utility of the KFRE score.
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